HiGHS is a high performance serial and parallel solver for large scale sparse linear optimization problems of the form $$ \min \quad \dfrac{1}{2}x^TQx + c^Tx \qquad ...

Colorectal cancer cells display key features such as metabolizing glucose at high rates, and escaping immune surveillance. However, how these two features are linked at molecular levels is largely ...

Introduction Reviewing and updating research priorities is essential to assess progress and to ensure optimal allocation of financial and human resources in research. In 2001, WHO held a research ...

1 Department of Mathematics, University of Patras, Patras, Greece. 2 Department of Business Administration, University of Patras, Patras, Greece. This paper presents a new dimension reduction strategy ...

1 Department of Basic Sciences and Humanities, University of Asia Pacific, Dhaka, Bangladesh. 2 General Education Department, City University, Dhaka, Bangladesh. 3 Department of Mathematics, ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. The thiourea–iodate reaction has been investigated simultaneously by ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. No ...

Another of the most commonly studied GDEPTs is the Cytosine Deaminase (CD) suicide gene system, which deaminases the prodrug, 5-fluorocytosine, into 5-fluorouracil, and causes death through a similar ...

Herpes simplex virus (HSV) can infect a broad host range and cause mild to life threating infections in humans. The surface glycoproteins of HSV are evolutionarily conserved and show an extraordinary ...

Herpes simplex virus-1 (HSV-1) establishes a latent infection in neurons and periodically reactivates to cause disease. The stimuli that trigger HSV-1 reactivation have not been fully elucidated. We ...