Pythons' extreme biology may hold clues for treating human disease

These snakes can go for months without eating, grow and shrink the size of their hearts and jump start their metabolism on a ...

I loved ChatGPT Desktop until OpenAI gutted it to make room for Codex and Work

OpenAI just merged the ChatGPT desktop app with Codex - and removed my favorite productivity features. What were they ...
Hackaday

MicroPython Is This Summer’s Hottest Title For The SNES, Thanks To Claude Fable

MicroPython, for the uninitiated, is a pared-down version of python meant to run on today’s powerful microcontollers. As ...
Frontiers

pyTCR: A comprehensive and scalable solution for TCR-Seq data analysis to facilitate reproducibility and rigor of immunogenomics research

T cell receptor (TCR) studies have grown substantially with the advancement in the sequencing techniques of T cell receptor repertoire sequencing (TCR-Seq). The analysis of the TCR-Seq data requires ...
GitHub

Batch downloading FASTQ files using the SRA toolkit, fastq-dump, and Python

Most scientific journals require scientists to make their sequencing data publicly available. This way, other researchers in the world can download the raw data and ...
Frontiers

NUMT Confounding Biases Mitochondrial Heteroplasmy Calls in Favor of the Reference Allele

Homology between mitochondrial DNA (mtDNA) and nuclear DNA of mitochondrial origin (nuMTs) causes confounding when aligning short sequence reads to the reference human genome, as the true sequence ...
GitHub

A module for working with snap files in Python.

snap (Single Nucleus Accessibility Profile) file is a hierarchically structured hdf5 file that is specially designed for storing single nucleus ATAC-seq datasets. A snap file (version 4) contains the ...
Europe PMC

fastp: an ultra-fast all-in-one FASTQ preprocessor.

Quality control and preprocessing of FASTQ files are essential to providing clean data for downstream analysis. Traditionally, a different tool is used for each operation, such as quality control, ...