Supervised hierarchical clustering based on the top 200 differentially expressed genes showed distinct clustering of the majority of autism cortex samples (Fig. 1a), including one case that was ...
Each substrate forms a 10-base-pair (bp) duplex with nucleotides 2–11 of the 12-nucleotide guide counted from box D/D′. The guide–substrate duplexes are placed in an RNA-binding channel formed by the ...