Discovery of new compounds that ameliorate the negative health impacts of aging promises to be of tremendous benefit across a number of age-based comorbidities. One method to prioritize a testable ...

School of Information Science and Engineering, Northeastern University, Shenyang 110819, China Liaoning Key Laboratory of Intelligent Diagnosis and Safety for Metallurgical Industry, Northeastern ...

The genomes of cytoplasmic organelles (mitochondria and plastids) are maternally inherited in most eukaryotes, thus excluding organellar genomes from the benefits of sexual reproduction and ...

GAHP is a freely available software package for genetic analysis with bi-parental immortalized heterozygous and pure-line populations. The package is project-based and integrated with multiple ...

Department of Electrical Engineering, City University of Hong Kong, Kowloon, Hong Kong 999077 Centre for Biosystems, Neuroscience, and Nanotechnology, City University of Hong Kong, Kowloon, Hong Kong ...

The intricate folding of the mitochondrial inner membrane is essential for the functioning of mitochondria as cellular powerhouses. The mitochondrial contact site and cristae organizing system (MICOS) ...

Genome-wide screening using CRISPR coupled with nuclease Cas9 (CRISPR-Cas9) is a powerful technology for the systematic evaluation of gene function. Statistically principled analysis is needed for the ...

To help protect the body from disease, small immune cells called T lymphocytes move rapidly, searching for signs of infection. These signs are antigens – processed pieces of proteins from invading ...

This is how the future arrived. It began innocuously, in the early 2000s, when businesses started to realize that highly skilled jobs formerly performed in-house, by a single employee, could more ...

Advances in the imaging of biological structures with transmission electron microscopy continue to reveal information at the nanometer length scale and below. The images obtained are static, i.e., ...