Researchers have developed a new computational approach that enables more accurate selection of genes that characterize ...

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Coronary atherosclerotic plaques susceptible to acute coronary syndrome have traditionally been characterized by their surrounding cellular architecture. However, with the advent of intravascular ...

Developmental programming involves the accurate conversion of signalling levels and dynamics to transcriptional outputs. The transcriptional relay in the Notch pathway relies on nuclear complexes ...

Proper differentiation of sperm from germline stem cells, essential for production of the next generation, requires dramatic changes in gene expression that drive remodeling of almost all cellular ...

Machine learning (ML) and in particular deep learning techniques have gained popularity for predicting structures from biopolymer sequences. An interesting case is the prediction of RNA secondary ...

Deep learning, or artificial neural networks, is a type of machine learning algorithm that can decipher underlying relationships from large volumes of data and has been successfully applied to solve ...

Omes and omics are proliferating these days: Genomics. Proteomics. Metabolomics. But what are they? What’s the point of ome-ing everything? An “ome” is a totality. So a genome is all the DNA, ...

Researchers have demonstrated a new approach to joining -- and reconfiguring -- modular DNA building units, by snapping together complementary shapes instead of zipping together strings of base pairs.

A pseudoknot forms in an RNA when nucleotides in a loop pair with a region outside the helices that close the loop. Pseudoknots occur relatively rarely in RNA but are highly overrepresented in ...