PC1 (polycystin-1), traditionally viewed through the lens of renal pathophysiology in autosomal dominant polycystic kidney disease, has emerged as a central regulator of cardiovascular mechanobiology.

Today:Early fog in the far southwest clears quickly. Most areas stay dry with sunshine and variable cloud, though northern and northeastern regions may see isolated showers. Light winds overall, ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. Data-driven ...

Laboratory for Sensors, IMTEK − Department of Microsystems Engineering, University of Freiburg, 79110 Freiburg, Germany Laboratory for Electrical Instrumentation and Embedded Systems, IMTEK − ...

Discovering the rules of synaptic plasticity is an important step for understanding brain learning. Existing plasticity models are either (1) top-down and interpretable, but not flexible enough to ...

Genetically-encoded combinatorial peptide libraries are convenient tools to identify peptides to be used as therapeutics, antimicrobials and functional synthetic biology modules. Here, we report the ...

Close-packed hexagonal array nanopores are widely used both in research and industry. A self-ordered nanoporous structure makes anodic aluminum oxide (AAO) one of the most popular nanomaterials. This ...

Hypoxia promotes renal damage and progression of chronic kidney disease (CKD). The erythrocyte is the only cell type for oxygen (O 2) delivery. Sphingosine 1-phosphate (S1P)—a highly enriched biolipid ...

We report that a previously uncharacterized protein genetically associated with cytoplasmic chemoreceptors of undefined function senses both iron and oxygen to mediate chemotaxis. Spectroscopic and ...