Spatial EcoTyper is a versatile framework for identifying spatially distinct multicellular communities, termed spatial ecotypes, from single-cell spatial transcriptomics data. In addition, it provides ...

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Department of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, California 90048, United States Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, ...

“Hey model, if I prompt you with the marker genes for a cell type, can you complete the transcription factors that you believe would be highly expressed with expression of these genes?” posed ...

This study makes a valuable contribution to spatial transcriptomics by rigorously benchmarking cell-type deconvolution methods, assessing their performance across diverse datasets with a focus on ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Mass spectrometry (MS) enables specific and accurate quantification of proteins with ...

This tutorial will showcase analysis of single-cell RNA sequencing data following the tidy data paradigm. The tidy data paradigm provides a standard way to organise data values within a dataset, where ...

Intracranial non-branching site blood blister-like aneurysms (BBA) are extremely rare and vicious. Their etiology remains elusive, and no molecular study has been carried out to reveal its pathogenic ...

The development of innovative single-cell technologies has allowed the high-dimensional transcriptomic and proteomic profiling of individual blood and tissue cells. Recent single-cell studies revealed ...

The mouse is the most important animal model within neuroscientific research, a position strengthened by the wide-spread use of transgenic mouse models. Discoveries in animals are followed by ...