Some signals help the tumor grow, while others help the immune system fight back. The same signal can thus mean different things in different cells. One example is the JAK-STAT pathway. It helps cells ...

Researchers at the Icahn School of Medicine at Mount Sinai have identified the immune cell that acts as the architect and ...

Subscribe to our newsletter for the latest sci-tech news updates. The study, published today in Cancer Cell, generated spatial transcriptomic maps in precancerous and more advanced stages of lung ...

Background Pancreatic ductal adenocarcinoma (PDAC) is largely refractory to immune checkpoint blockade, owing to its ...

True three-dimensional (3D) spatial biology provides a more physiologically relevant view of tissue biology and cellular interactions than conventional single-cell or two-dimensional (2D) thin-tissue ...

Every day, billions of people travel from their homes to work, schools, health care facilities, restaurants, public venues ...

Contributed by Howard Y. Chang; received November 19, 2024; accepted February 20, 2025; reviewed by Jellert Gaublomme and David A. Quigley The spatial organization of cells within tissues plays a ...

Overall, this work highlights the potential of spatial transcriptomics to capture early, context-dependent molecular changes in OED. Further validation and higher-resolution studies will be required ...

Cloning articles. Uncover cloned animal abnormalities, discover cloned pigs with benefits such as omega-3 fatty acids and much more in our current research news on cloning.