DNA is often called the blueprint of life, but what does that really mean? Elizabeth Worthey, Ph.D., associate professor, Department of Genetics in the Heersink School of Medicine, explains everything ...
Scientists show DNA polymerases can build long, patterned DNA without a template, opening new paths for synthetic biology and ...
In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...
Our DNA is made of millions of combinations of the genomes that create the human body. Even the smallest changes in these sequences, or in how they act, can change the functioning of the whole body ...
The Pol-theta enzyme (blue) joins two parts of a broken DNA strand (yellow). This process is mutagenic and can give rise to cancer. LA JOLLA, CA—DNA repair proteins act like the body’s editors, ...
Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists as part of a DNA-protein complex known as chromatin. For this purpose, the ...
CLEVELAND—DNA isn’t just a long string of genetic code, but an intricate 3D structure folded inside each cell. That means the tools used to study DNA need to be just as sophisticated—able to read not ...
DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...
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