The tiny little powerhouses of our cells, the mitochondria, are unique among organelles because they carry their own tiny ...

According to a recent AHA Scientific Statement, despite ongoing limitations, recent advances in genomic sequencing ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in nuclear DNA. These lesions disrupt energy production and activate ...

One study reported 8 live births from 22 women with pathogenic mtDNA variants who underwent mitochondrial donation through pronuclear transfer. None had signs of mitochondrial disease and heteroplasmy ...

Provide each team with a copy of "The Hunt for mtDNA" student handout. Explain to students what mtDNA is, how it differs from nuclear DNA, and how it is inherited (see Activity Answer for more ...

There are a total of 5 multi-subunit complexes in the inner membrane of the mitochondria, all of which are involved in the process of oxidative phosphorylation that precedes ATP production. Of these, ...

When it comes to identification with DNA, forensic scientists have two basic approaches at their disposal. One approach analyzes nuclear DNA and is useful in identifying someone who is alive or has ...

Mitochondrial donation through pronuclear transfer resulted in several live births and reduced transmission of pathogenic mitochondrial DNA (mtDNA) variants, researchers reported. The study involved ...