Four astronauts, including two from NASA, are set to leave the International Space Station on Wednesday, weeks earlier than planned, due to a medical issue.

After NASA conducted its first medical evacuation from the International Space Station, the astronauts are expected to splashdown near San Diego.

This photo provided by NASA shows clockwise from bottom left are, NASA astronaut Mike Fincke, Roscosmos cosmonaut Oleg Platonov, NASA astronaut Zena Cardman, and JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui gathering for a crew portrait wearing their Dragon pressure suits during a suit verification check inside the International Space Station’s Kibo laboratory module,

A crew of four astronauts departed the International Space Station on Wednesday in NASA’s first-ever medical evacuation following an undisclosed ailment with one of the crew members.

SpaceX's Crew-11 astronauts will leave the International Space Station today (Jan. 14) in the first-ever medical evacuation from the orbiting lab, and you can watch it live.

Space Station in NASA’s first medical evacuation. Posted: January 15, 2026 \. Former NASA Astronaut Leroy Chiao joins The Lead

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The medical evacuation from the space station is underway, with four astronauts in their spaceship heading back to Earth so one of them can receive medical treatment. NBC News’ Tom Costello has the latest.