A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

An international research team reveals new molecular mechanisms associated with pathogenic mutations in the protein ...

In a recent study published in Scientific Reports, researchers used multiple publically available cancer sequencing project datasets encompassing 20,331 primary tumor genomic sequences representing 41 ...

Researchers found a way to screen cancer-linked gene mutations much more easily and quickly than existing approaches, using a variant of CRISPR genome-editing known as prime editing. Tumors can carry ...

Deafness, the most common sensorineural hearing loss at all stages of life, occurs either independently or as part of ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

A lung cancer diagnosis can feel frightening. And when a family member is diagnosed, you might wonder about your own risk, prompting you to ask if lung cancer is hereditary. Smoking tobacco accounts ...