PanMAN data structures compress pangenomes massively, encode evolutionary histories, and enable scalable analysis of millions of genomes.

Genetic variation describes naturally occurring genetic differences among individuals of the same species. This variation permits flexibility and survival of a population in the face of changing ...

Researchers at the University of California have created a novel data structure and compression method that allows ...

A number of studies have highlighted that ethnicity is an important factor influencing the genetic variability of some CYP450 enzymes and that human adaptation could have a role in shaping the genetic ...

Engineers at UC San Diego have developed a new data structure and compression technique that enables the field of pangenomics ...

Knowing how human DNA changes over generations is essential to estimating genetic disease risks and understanding how we evolved. But some of the most changeable regions of our DNA have been ...

There are a number of C. trachomatis gene products that exhibit variability and may modulate disease severity (Figure 3). The major categories of variable chlamydial gene products and their roles in ...

Blood cancer is an umbrella term for a variety of diseases that affect the blood, bone marrow and lymphatic system. Like most ...

A new study from the NIH’s All of Us program is shaking up long-held assumptions by revealing that genetic ancestry rarely aligns with racial labels — and that the interplay between biology and ...