This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).

61 codons specify one of the 20 amino acids that make up proteins 3 codons are stop codons, which signal the termination of protein synthesis Importantly, the genetic code is nearly universal, shared ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...

By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes ...

The genetics of a marine protozoan may overturn one of the long-held tenets of protein synthesis. According to conventional wisdom, the genetic code is unambiguous: each DNA triplet, or codon, ...

The beauty of the DNA code is that organisms interpret it unambiguously. Each three-letter nucleotide sequence, or codon, in a gene codes for a unique amino acid that’s added to a chain of amino acids ...

The same amino acid can be encoded by anywhere from one to six different strings of letters in the genetic code. Andrzej Wojcicki/Science Photo Library via Getty Images Nearly all life, from bacteria ...

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...

There were characteristic modes of discordance between ZAP-70 and VH mutation status depending on the presence or absence of additional genetic high-risk features such as 11q and 17p deletion or V3-21 ...