Internal acid–base homeostasis is fundamental for maintaining life. Accurate and timely interpretation of an acid–base disorder can be lifesaving, but the establishment of a correct diagnosis may be ...

Antibiotics are among the most frequently prescribed drugs in medicine. Their use, however, is often limited by associated renal toxic effects. The most common manifestation of these toxic effects is ...

The article by Berend et al. 1 in this issue of the Journal is the first in a series of review articles that consider approaches to the understanding and management of fluid, electrolyte, and ...

Acute metabolic acidosis is associated with increased morbidity and mortality because of its depressive effects on cardiovascular function, facilitation of cardiac arrhythmias, stimulation of ...